Longevity & Mitochondrial Peptides
Explore peptides studied in mitochondrial function, cellular stress, senescence and healthy-aging research. These profiles emphasize the gap between mechanistic plausibility and demonstrated human outcomes.
Educational research reference only, not medical advice. Evidence strength and regulatory status vary substantially between compounds.
8 research profiles
Epithalon
Epithalon, also spelled Epitalon or Epithalone, is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG). It is most often discussed in longevity communities because of its association with pineal…
Read profile →FOXO4 and FOXO4-DRI
FOXO4-DRI is a senolytic peptide concept designed to interfere with survival signaling in senescent cells. The goal is selective removal of damaged cells that resist apoptosis, not general stimulation. Evidence lens…
Read profile →Humanin
Humanin is a small peptide made from a short open reading frame inside the mitochondrial 16S rRNA region. It is best understood as a cellular stress-response and survival signal, not as an approved anti-aging injection.…
Read profile →MOTS-c
MOTS-c is a 16-amino-acid mitochondrial-derived peptide. It is discussed as an “exercise mimetic” or metabolic-signaling peptide because it is linked to skeletal-muscle metabolism, AMPK-related pathways, insulin…
Read profile →NAD+
NAD+ is a coenzyme involved in energy metabolism, sirtuin activity, DNA repair, and cellular stress responses. It appears in peptide-clinic settings because it is often injected or infused, not because it is chemically a…
Read profile →Pinealon
Pinealon is a short EDR tripeptide discussed for neuroprotection, cognitive aging, and bioregulator concepts. Evidence lens: Most support is preclinical, small, regional, or mechanistic. The guide should not present it…
Read profile →SS-31
SS-31, now approved as elamipretide under the FORZINITY label, targets cardiolipin in the inner mitochondrial membrane. The approved use is narrow. Evidence lens: Approval scope matters. Evidence supporting accelerated…
Read profile →Vilon
Vilon is a two-amino-acid peptide: lysine plus glutamic acid, abbreviated Lys-Glu or KE. It is usually marketed as a thymus/immune-aging bioregulator. It is not the same as thymosin alpha-1, thymalin, thymogen, or…
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