Weight Loss & Metabolic Peptides

Compare approved and investigational metabolic peptides, including GLP-1, GIP, glucagon and amylin-pathway compounds. Profiles separate product-label evidence from clinical trials, preclinical findings and community reports.

Educational research reference only, not medical advice. Evidence strength and regulatory status vary substantially between compounds.

9 research profiles

5-Amino-1MQ

5-Amino-1MQ is included because peptide clinics and metabolic-stacking discussions often mention it, but chemically it is not a peptide. It is usually discussed as an NNMT inhibitor related to fat-cell metabolism and NAD…

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Adipotide

Adipotide is a targeted pro-apoptotic fat-vasculature compound. The animal data are notable, especially the obese-rhesus-monkey study, but the mechanism is tissue injury rather than reversible hormone signaling. Human…

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AOD-9604

AOD-9604 is a modified fragment of human growth hormone intended to isolate fat-metabolism signaling without full hGH activity. Evidence lens: It has more human safety context than many gray-market peptides, but that is…

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Cagrilintide

Cagrilintide is an amylin analog. In the CagriSema combination, it is paired with semaglutide so that one component strengthens satiety/satiation signaling while the GLP-1 component reduces appetite and improves glycemic…

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HGH Fragment 176-191

HGH Fragment 176-191 is a short C-terminal portion of the growth hormone molecule promoted for fat metabolism. It is not full growth hormone and should not be treated as the same product as AOD-9604. Evidence lens: Many…

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Retatrutide

Retatrutide activates GLP-1, GIP, and glucagon receptors. The glucagon component is the key differentiator from tirzepatide and may contribute to greater energy-expenditure and liver-fat effects, but it may also change…

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Semaglutide

Semaglutide is a GLP-1 receptor agonist with approved uses in diabetes, obesity/weight management, and cardiovascular-risk contexts depending on product and label. It is not a research peptide in the same sense as…

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Tesamorelin

Tesamorelin is an approved GHRH analog used to reduce excess visceral abdominal fat in adults with HIV-associated lipodystrophy. It is not simply a generic belly-fat peptide for everyone. Evidence lens: The approved…

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Tirzepatide

Tirzepatide is a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, with additional label expansion depending on current product status. It is a prescription drug, not a…

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